Probably. Almost all of those suffered doomsday scenarios though, do I think that’s going to happen to MTG/Pokemon (the core of my collectables) in the next 10 years? No. Is it possible? Of course but that’s a risk I’ve assessed and I’m willing to bet against.
When it comes to my collection, this is the way I look at it. I only buy things I’m interested in. 90% because of the personal value the card/product has to me. 10% because of monetary value. I can always make more money. They are not making anymore WOTC Pokémon cards though!!